Nucleosides and Analogues
![Alkali Scientific ATP [Adenosine 5' triphosphate, disodium salt trihydrate], 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660442.jpg-250.jpg)
Alkali Scientific ATP [Adenosine 5' triphosphate, disodium salt trihydrate], 10 G
ATP (Adenosine 5' triphosphate, disodium salt trihydrate) is a high-purity energy molecule used in various laboratory applications. This 10G package is ideal for large-scale experiments in enzymology, cell signaling, and protein synthesis. ATP is essential in driving numerous biochemical reactions, acting as a primary source of energy for cellular functions such as DNA replication, protein synthesis, and muscle contraction. It is commonly used in assays that involve ATPase activity, in vitro transcription, and in studying cellular processes requiring energy input. This ATP reagent is widely used in molecular biology, biochemistry, and biophysical research.
Apexbio Technology LLC 2-Amino-ATP(Synonyms: 2-NH2-ATP, 2-Aminoadenosine triphosphate, 2-Amino-adenosine-5'-triphosphate, 2-Amino-ATP (free acid)), 10ul (100 mM).
2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
AdipoGen Guanosine 5-triphosphate Na
Chemical. CAS 36051-31-7. Formula C10H16N5O14P3 . xNa. Molecular Weight 523.18 free acid basis. Guanosine 5-triphosphate GTP trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. GTP is involved in the initiation of peptide synthesis during the binding of formylmethionyl-tRNA F-met-tRNA to the ribosome. It is also involved in polypeptide chain elongation.
![eMolecules 74804-12-9 | Adenosine 5'-triphosphate magnesium salt | Combi-Blocks | MFCD00084767 | 529.470 | C10H14MgN5O13P3 | 95.000 | [Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O | 1g | 388718358](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502212903.JPG-250.jpg)
eMolecules 74804-12-9 | Adenosine 5'-triphosphate magnesium salt | Combi-Blocks | MFCD00084767 | 529.470 | C10H14MgN5O13P3 | 95.000 | [Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O | 1g | 388718358
Adenosine 5'-triphosphate magnesium salt | Combi-Blocks | 74804-12-9 | MFCD00084767 | 529.470 | C10H14MgN5O13P3 | 95.000 | [Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O | 1g | 388718358
Medchemexpress LLC Phosphoramidon disodium | 164204-38-0 | MFCD00077870 | 99.8% | 587.47 | C23H32N3Na2O10P | 10 MG
Phosphoramidon disodium is a microbial metabolite and metalloprotease inhibitor used as a research reagent to study metallopeptidases. It potently inhibits thermolysin (IC50 ≈ 0.4 μg/mL) and shows activity against endothelin-converting enzyme, neutral endopeptidase, and angiotensin-converting enzyme.
- High purity: 99.8% (typical, datasheet)
- White to off-white solid suitable for biochemical assays
- Soluble in water (≥140 mg/mL) and DMSO (100 mg/mL; sonication recommended)
- Storage: store sealed at 4°C; in solution store -80°C (up to 6 months) or -20°C (up to 1 month)
- Supplied in small research quantities, typically 10 mg
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5 betagama imi100MG
Guanosine 5prime-[beta gamma-imido]triphosphate (GMP-PNP Gpp(NH)p) is a non-hydrolyzable analog of GTP that binds and irreversibly activates G proteins. Gpp(NH)p is used in a variety of applications that involve GTP binding including GTP-activation GTP-inhibition GTP transport GTP hydrolysis and GTP structure stabilization. Since a cycle of GTP binding hydrolysis and release is required for the initiation of protein translocation across the endoplasmic reticulum guanosine 5prime-[beta gamma-imido]triphosphate is often used in studies of protein synthesis. Gpp(NH)p is used to activate ADP-ribosylation factors and to modulate G proteins involved in cell signaling protein synthesis and other metabolic processes.
Sigma Aldrich Fine Chemicals Biosciences Adenosine Deaminase from b
Molecular weight 32.5-33 kDapI 4.85
Medchemexpress LLC ATP-polyamine-biotin | 1800401-93-7 | MFCD29924712 | >98.0% | 945.85 g/mol | C32H58N11O14P3S | 10 MG
ATP-polyamine-biotin is a cell-permeable ATP analogue used as an efficient kinase co-substrate to transfer a biotin tag to kinase substrates in vitro and in live cells. It facilitates detection and enrichment of phosphorylated proteins for downstream analysis in biochemical and cell-based assays.
- Promotes biotin labeling of kinase substrates in live cells.
- Functions as an efficient ATP cosubstrate for kinases.
- Enables detection and enrichment of phosphorylated proteins.
- Provided with high purity suitable for biochemical assays.
- Available in multiple pack sizes, including 10 mg.
Apexbio Technology LLC ATP(Synonyms: Adenosine triphosphate, Adenosine 5'-triphosphate, Adenosine-5'-triphosphoric acid), 500mg, CAS: 56-65-5.
Adenosine triphosphate (ATP CAS 56-65-5) is a nucleoside triphosphate comprising adenine linked to ribose with three phosphate groups esterified sequentially ATP primarily functions as a universal energy carrier in cellular metabolism transferring phosphate groups to facilitate enzymatic reactions and drive biological activities Additionally ATP acts extracellularly as a neurotransmitter and signaling molecule binding purinergic receptors to modulate physiological responses such as neurotransmission vascular tone inflammation and immune cell function Due to its versatile biological roles ATP is extensively employed in biomedical research investigating metabolic pathways receptor signaling dynamics and cellular energetics
Sigma Aldrich Fine Chemicals Biosciences Adenosine 99100G
In the extracellular space ecto-5AE-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation.
Medchemexpress LLC GTP-14564 | 34823-86-4 | MFCD01416326 | 99.9% | 234.25 g·mol⁻¹ | C15H10N2O | 5 MG
GTP-14564 is a small-molecule tyrosine kinase inhibitor selective for internal tandem duplication (ITD) mutant and wild-type FLT3. It inhibits FLT3 ligand-dependent proliferation of Ba/F3 leukemia cells and is used as a research tool to study FLT3-driven signaling and leukemogenesis. Chemical formula C15H10N2O; molecular weight 234.25 g·mol⁻¹; reported purity 99.91%.
- Targets ITD and wild-type FLT3.
- Inhibits FLT3 ligand-dependent growth in Ba/F3 cells.
- High reported purity suitable for biochemical assays.
- Compact quantity suitable for screening and small-scale studies.
- Documented in chemical databases and literature for FLT3 research.
Apexbio Technology LLC 2'-O-Methyl-N6-Methyl-ATP 50ul (100 mM)
2p-O-Methyl-N6-Methyl-ATP is a chemically modified ATP analog bearing methyl substitutions at the N6 position of adenine and the 2 -hydroxyl group of the ribose sugar 2p-O-Methyl-N6-Methyl-ATP is designed to facilitate the study of RNA methylation processes and RNA protein interactions supporting the mechanistic exploration of RNA-modifying enzymes and epigenetic regulatory pathways Based on these properties 2p-O-Methyl-N6-Methyl-ATP holds research potential in investigations of ligand RNA interactions and drug discovery applications targeting RNA-related biological processes
Medchemexpress LLC AZT triphosphate tet 10mg | 106060-92-8 | 10 MG
AZT triphosphate tetraammonium is the tetraammonium salt of the active triphosphate metabolite of zidovudine (AZT). It is used as a biochemical reagent in virology and nucleotide metabolism studies where the active nucleotide analog is required. The product is supplied with a certificate of analysis and safety data sheet and is intended for research use only.
- Active triphosphate metabolite of zidovudine (AZT) for biochemical assays.
- High chemical purity suitable for analytical and cellular studies.
- Available as a solid in multiple milligram sizes and as a 10 mM solution in DMSO.
- Supplied with certificate of analysis and safety data sheet for quality and handling information.
- Recommended storage: sealed at -20°C; in solvent store at -80°C for up to 6 months.
![Medchemexpress LLC 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(5-chloro-2-thienyl)sulfonyl]-1-phenyl- | 1023043-30-2 | 99.6% | 411.93 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439112-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(5-chloro-2-thienyl)sulfonyl]-1-phenyl- | 1023043-30-2 | 99.6% | 411.93 | 25 MG
ATP synthase inhibitor 1 is a potent inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening but does not affect ATP levels.
- Potent inhibitor of c subunit of the F1/FO-ATP synthase complex
- Inhibits mitochondrial permeability transition pore (mPTP) opening
- Does not affect ATP levels
Medchemexpress LLC TFEB Decoy ODN sodium | 90.2% | 1 MG
TFEB Decoy ODN sodium is a synthetic oligonucleotide featuring a hairpin ring structure, engineered to inhibit Transcription factor EB (TFEB). It has demonstrated efficacy in inhibiting fibrosis and autophagy within a UUO mouse model, and also exhibits anti-inflammatory effects.
- Synthetic oligonucleotide with a hairpin ring structure.
- Designed to inhibit transcription factor EB (TFEB).
- Inhibited fibrosis in a UUO mouse model.
- Inhibited autophagy in a UUO mouse model.
- Showed anti-inflammatory effects.